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Coconut Research
The journal articles listed
below are just a small sampling of the many published studies involving
coconut oil, medium-chain triglycerides, and other related subjects.
Quick
links to research categories on this page:
Antimicrobial Effects
Cardiovascular Health
Cancer
Diabetes
Digestion and Nutrient
Absorption
Epilepsy
Hospital Patient Care/Enteral and Parenteral Nutrition
Metabolism/Energy
Weight
Management
HIV/AIDS, Liver Disease,
and Other Health Concerns
Antimicrobial Effects
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The Effect Of Virgin Coconut Oil Supplementation For Community-Acquired
Pneumonia In Children Aged 3 To 60 Months Admitted At The Philippine
Children's Medical Center: A Single Blinded Randomized Controlled Trial,
CHEST, October 29, 2008
In vitro antimicrobial properties of coconut oil on Candida species in
Ibadan, Nigeria.
J Med Food. 2007 Jun;10(2):384-7
Antimicrobial Activity of Saturated Fatty Acids and Fatty Amines against
Methicillin-Resistant Staphylococcus aureus,
Biological & Pharmaceutical Bulletin, Vol. 27 (2004) , No. 9 1321
Antibacterial actions of fatty acids and monoglycerides against
Helicobacter pylori. FEMS Immunol Med Microbiol. 2003 May
15;36(1-2):9-17.
Bactericidal effects of fatty acids and monoglycerides on Helicobacter
pylori. Int J Antimicrob Agents. 2002 Oct;20(4):258-62.
Effect of fatty acids on arenavirus replication: inhibition of virus
production by lauric acid. Arch Virol. 2001;146(4):777-90.
Killing of Gram-positive cocci by fatty acids and monoglycerides. APMIS.
2001 Oct;109(10):670-8.
In vitro killing of Candida albicans by fatty acids and monoglycerides.
Antimicrob Agents Chemother. 2001 Nov;45(11):3209-12.
In vitro susceptibilities of Neisseria gonorrhoeae to fatty acids and
monoglycerides. Antimicrob Agents Chemother. 1999 Nov;43(11):2790-2.
Medium-chain triglycerides inhibit growth of Malassezia: implications
for prevention of systemic infection. Crit Care Med. 1999
Sep;27(9):1781-6.
In vitro inactivation of Chlamydia trachomatis by fatty acids and
monoglycerides. Antimicrob Agents Chemother. 1998 Sep;42(9):2290-4.
Susceptibility of Helicobacter pylori to bactericidal properties of
medium-chain monoglycerides and free fatty acids. Antimicrob Agents
Chemother. 1996 Feb;40(2):302-6.
Inactivation of enveloped viruses in human bodily fluids by purified
lipids. Ann N Y Acad Sci. 1994 Jun 6;724:457-64. Review.
Inactivation of visna virus and other enveloped viruses by free fatty
acids and monoglycerides. Ann N Y Acad Sci. 1994 Jun 6;724:465-71.
Lauric acid inhibits the maturation of vesicular stomatitis virus. J Gen
Virol. 1994 Feb;75 ( Pt 2):353-61.
Antibacterial effect of caprylic acid and monocaprylin on major
bacterial mastitis pathogens. J Dairy Sci. 2005 Oct; 88(10):3488-95.
Inactivation of enveloped viruses and killing of cells by fatty acids
and monoglycerides. Antimicrob Agents Chemother. 1987 Jan;31(1):27-31.
The effects of fatty acids and their monoesters on the metabolic
activity of dental plaque. J Dent Res. 1984 Jan;63(1):2-5.
Cardiovascular Health
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Note: A large number of studies are showing a direct correlation between
chronic low-grade bacterial and viral infections and coronary heart
disease. The primary culprits are Chlamydia pneumoniae, Cytomegalovirus,
and Helicobacter pylori. Each of these pathogenic organisms as well as
many others are effectively killed by the medium-chain fatty acids in
coconut oil. Coconut oil, therefore, can reduce risk of heart disease.
Effects of dietary coconut oil on the biochemical and anthropometric
profiles of women presenting abdominal obesity. Lipids. 2009
Jul;44(7):593-601. Epub 2009 May 13.
Medium chain triglyceride oil consumption as part of a weight loss diet
does not lead to an adverse metabolic profile when compared to olive
oil. J Am Coll Nutr. 2008 Oct;27(5):547-52.
Effects of dietary medium-chain triglyceride on weight loss and insulin
sensitivity in a group of moderately overweight free-living type 2
diabetic Chinese subjects. Metabolism. 2007 Jul;56(7):985-91.
Beneficial effects of virgin coconut oil on lipid parameters and in
vitro LDL oxidation. Clin Biochem. 2004 Sep;37(9):830-5
Comparative Study of Coconut Oil, Soybean Oil, and Hydrogenated Soybean
Oil. PJCS. 2004;24
A diet rich in coconut oil reduces diurnal postprandial variations in
circulating tissue plasminogen activator antigen and fasting lipoprotein
(a) compared with a diet rich in unsaturated fat in women. J. Nutr.
2003;133:3422-3427.
Antibiotic treatment of atherosclerosis. Curr Opin Lipidol. 2003
Dec;14(6):605-14.
Coconut
Oil: Atherogenic or Not? (What therefore causes Atherosclerosis?).
Philippine Journal of Cardiology. 2003 July-Sept; 31(3):97-104.
Chronic infection and coronary artery disease. Cardiol Clin. 2003
Aug;21(3):333-62.
Prevalence of Chlamydia pneumoniae in the atherosclerotic plaque of
patients with unstable angina and its relation with serology. Int J
Cardiol. 2003 Jun;89(2-3):273-9.
Effects of dietary medium-chain triacylglycerols on serum lipoproteins
and biochemical parameters in healthy men.
Biosci Biotechnol Biochem. 2002 Aug;66(8):1713-8
Results of use of metformin and replacement of starch with saturated fat
in diets of patients with type 2 diabetes. Endocr Pract. 2002
May-Jun;8(3):177-83.
Secondary prevention of coronary artery disease with antimicrobials:
current status and future directions. Am J Cardiovasc Drugs.
2002;2(2):107-18.
Chronic infections and atherosclerosis. J Med Assoc Thai. 2001 Dec;84
Suppl 3:S650-7.
Emerging relations between infectious diseases and coronary artery
disease and atherosclerosis. CMAJ 2000 Jul 11;163(1);49-56.
The possible role of human cytomegalovirus (HCMV) in the origin of
atherosclerosis. J Clin Virol 2000 Feb;16(1):17-24.
Effects of total pathogen burden on coronary artery disease risk and
C-reactive protein levels. Am J Cardiol 2000 Jan 15;85(2):140-6.
A cross-over study of the effect of a single oral feeding of medium
chain triglyceride oil vs. canola oil on post-ingestion plasma
triglyceride levels in healthy men. Altern Med Rev 1999 Feb;4(1):23-8.
Inverse association of dietary fat with development of ischemic stroke
in men. JAMA 1997 December;278(24):2145-50.
The role of coconut and coconut oil in coronary heart disease in Kerala,
south India. Trop Doct. 1997 Oct;27(4):215-7.
Chronic infections and coronary heart disease: is there a link? Lancet,
1997 Aug;350(9075):430-37.
Review: nutritional support for patients with cirrhosis. J Gastroenterol
Hepatol. 1997 Apr;12(4):282-6.
Coconut oil consumption and coronary heart disease. Philipp J Intern
Med. 1992 May-Jun; 30(3):165-171.
Lipid patterns and dietary habits of healthy subjects living in urban,
suburban and rural areas. Ceylon Med J. 1991 Mar;36(1):9-16.
A reevaluation of coconut oil's effect on serum cholesterol and
atherogenesis. J Philipp Med Assoc. 1989 Jul-Sep; 65(1):144-152.
Coconut oil revisited. J Philipp Med Assoc. 1989 Jul-Sep; 65(1):140-142.
Medium chain triglycerides (MCT) in aging and arteriosclerosis. J
Environ Pathol Toxicol Oncol. 1986 Mar-Apr;6(3-4):115-21.
Medium chain triglycerides (MCT) in aging and arteriosclerosis. J
Environ Pathol Toxicol Oncol 1986 Mar-Apr;6(3-4):115-21.
Medium chain triglycerides (MCT) in aging and arteriosclerosis. J
Environ Pathol Toxicol Oncol. 1986 Mar-Apr;6(3-4):115-21.
Longitudinal analysis of the relationship between blood pressure and
migration: the Tokelau Island Migrant Study. Am J Epidemiol. 1985
Aug;122(2):291-301.
Cholesterol, coconuts, and diet on Polynesian atolls: a natural
experiment: the Pukapuka and Tokelau island studies. Am J Clin Nutr.
1981 Aug;34(8):1552-61.
The Tokelau Island Migrant Study: serum lipid concentration in two
environments. J Chronic Dis. 1981;34(2-3):45-55.
Chylothorax as a manifestation of rheumatic mitral stenosis: its
postoperative management with a diet of medium-chain triglycerides.
Chest 1978;73;672-673
Long-term effect of medium-chain triglyceride on hepatic enzymes
catalyzing lipogenesis and cholesterogenesis in rats. J Nutr Sci
Vitaminol (Tokyo). 1977;23(1):43-51.
Studies on Fatty Acid Composition of Adipose Tissue and Blood Lipids of
Polynesians. Am. J. Clin. Nutr. 1969 May; 22(5):594-605.
Effect of a saturated medium-chain triglyceride on serum-lipids in man.
Lancet. 1960 May 21;1(7134):1105-8.
Cancer
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Antitumor effect of medium-chain triglyceride and its influence on the
self-defense system of the body. Cancer Detect Prev. 1998;22(3):219-24.
Implementing a ketogenic diet based on medium-chain triglyceride oil in
pediatric patients with cancer. J Am Diet Assoc. 1995 Jun;95(6):693-7.
Effects of a ketogenic diet on tumor metabolism and nutritional status
in pediatric oncology patients: two case reports. J Am Coll Nutr. 1995
Apr;14(2):202-8.
Menhaden, coconut, and corn oils and mammary tumor incidence in BALB/c
virgin female mice treated with DMBA. Nutr Cancer. 1993;20(2):99-106.
A comparison of long-chain triglycerides and medium-chain triglycerides
on weight loss and tumour size in a cachexia model. Br J Cancer. 1988
Nov;58(5):580-3.
The influence of dietary medium chain triglycerides on rat mammary tumor
development. Lipids 1987 Jun;22(6):455-61.
Tumor promotion by dietary fat in azoxymethane-induced colon
carcinogenesis in female F344 rats: influence of amount and source of
dietary fat. J Natl Cancer Inst. 1984 Mar;72(3):745-50.
Influence of dietary medium-chain triglycerides on the development of N-methylnitrosourea-induced
rat mammary tumors. Cancer Res. 1984 Nov;44(11):5023-8.
Diabetes
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Medium-chain fatty acids ameliorate insulin resistance caused by
high-fat diets in rats. Diabetes Metab Res Rev. 2009 Feb;25(2):185-94.
Medium-chain fatty acids improve cognitive function in intensively
treated type 1 diabetic patients and support in vitro synaptic
transmission during acute hypoglycemia. Diabetes. 2009
May;58(5):1237-44. Epub 2009 Feb 17.
Effects of dietary medium-chain triglyceride on weight loss and insulin
sensitivity in a group of moderately overweight free-living type 2
diabetic Chinese subjects. Metabolism. 2007 Jul;56(7):985-91.
Results of use of metformin and replacement of starch with saturated fat
in diets of patients with type 2 diabetes. Endocr Pract. 2002
May-Jun;8(3):177-83.
Dietary substitution of medium-chain triglycerides improves
insulin-mediated glucose metabolism in NIDDM subjects. Diabetes. 1992
May;41(5):641-7.
Digestion and Nutrient
Absorption
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Short term effects of dietary medium-chain fatty acids and n-3
long-chain polyunsaturated fatty acids on the fat metabolism of healthy
volunteers. Lipids Health Dis. 2003 Nov 17;2(1):10.
Effects of medium- and long-chain triglycerides on sleep and
thermoregulatory processes in neonates. J Sleep Res. 1998 Mar;7(1):31-9.
Medium chain fatty acid metabolism and energy expenditure: obesity
treatment implications. Life Sci. 1998;62(14):1203-15.
Vegetable oil fortified feeds in the nutrition of very low birthweight
babies. Indian Pediatr. 1992 Dec;29(12):1519-27.
Neonatal hypoglycemia. Biol Neonate. 1990;58 Suppl 1:16-21.
Infant feeding formulas using coconut oil and the medium chain
triglycerides. J Am Coll Nutr. 1989 Jun;8(3):253-4.
Absorption of individual fatty acids from long chain or medium chain
triglycerides in very small infants. Am J Clin Nutr. 1986
May;43(5):745-51.
Chylous-fluid triglycerides and lipoproteins in a patient with
chylothorax put on a diet of butter or medium-chain triglyceride
[proceeedings]. Arch Int Physiol Biochim. 1980 Feb;88(1):B17-B19.
Regulation of hepatic fatty acid oxidation and ketone body production.
Annu Rev Biochem. 1980;49:395-420.
Chylothorax as a manifestation of rheumatic mitral stenosis: its
postoperative management with a diet of medium-chain triglycerides.
Chest 1978;73;672-673
Medium-chain triglyceride feeding in premature infants: effects on
calcium and magnesium absorption. Pediatrics. 1978 Apr;61(4):537-45.
MCT absorption by preterm infants. Nutr Rev. 1976 Mar;34(3):71-3.
Correction of the malabsorption of the preterm infant with a
medium-chain triglyceride formula. J Pediatr. 1975 Mar;86(3):446-50.
Medium-chain triglyceride feeding in premature infants: effects on fat
and nitrogen absorption. Pediatrics. 1975 Mar;55(3):359-70.
Correction of the malabsorption of the preterm infant with a
medium-chain triglyceride formula. J Pediatr. 1975 Mar;86(3):446-50.
Lactose-free, medium-chain triglyceride formulas in severe malnutrition.
Am J Dis Child. 1973 Sep;126(3):330-5.
Effect of medium chain triglyceride on fecal calcium losses in
pancreatic insufficiency. Clin Biochem. 1973 Jun;6(2):136-40.
The effect of medium-chain triglyceride on 47 calcium absorption in
patients with primary biliary cirrhosis. Gut. 1973 Aug;14(8):653-6.
The effects of medium-chain triglycerides in the short bowel syndrome.
Increased glucose and water transport. Am J Dig Dis. 1972
Mar;17(3):233-8.
Absorption of medium-chain triglycerides in animals with pancreatic
atrophy. Am J Dig Dis. 1972 Feb;17(2):129-37.
Medium Chain Triglycerides in Paediatric Practice. Arch Dis Child. 1970
August; 45(242): 445–452.
Coconut oil as a dietary source of fat with special reference to filled
milk. Hawaii Med J. 1969 Jul-Aug;28(6):459-63.
Assessment of Medium-chain Triglyceride Feeding in Infants with Cystic
Fibrosis. Arch. Dis. Childh., 1969, 44, 401.
Nutritional properties of medium-chain triglycerides. J Am Oil Chem Soc.
1968 Jan;45(1):19-22.
Epilepsy
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A randomized trial of classical and medium-chain triglyceride ketogenic
diets in the treatment of childhood epilepsy. Epilepsia. 2009
May;50(5):1109-17. Epub 2008 Nov 19.
Medium-chain triglyceride (MCT) ketogenic therapy. Epilepsia. 2008
Nov;49 Suppl 8:33-6.
Metabolic effects of three ketogenic diets in the treatment of severe
epilepsy. Dev Med Child Neurol. 1989 Apr;31(2):152-60.
Medium chain triglyceride diet
in the treatment of intractable childhood epilepsy. Arch Dis
Child. 1986 Dec;61(12):1168-72.
Early biochemical and EEG correlates of the ketogenic diet in children
with atypical absence epilepsy. Pediatr Neural 1985 Mar-Apr;1(2):104-8.
Medium-chain triglyceride (MCT) diet in intractable seizure disorders.
Neurology. 1985 Feb;35(2):237-8.
Monitoring octanoic and decanoic acids in plasma from children with
intractable epilepsy treated with medium-chain triglyceride diet. Clin
Chem. 1982 Apr;28(4 Pt 1):642-5.
Medium chain triglyceride oil ketogenic diets in the treatment of
childhood epilepsy. J Hum Nutr. 1978 Apr;32(2):111-6.
Medium-chain triglyceride diet in the treatment of intractable childhood
epilepsy. Dev Med Child Neurol. 1978 Apr;20(2):249-50.
Medium-chain triglycerides in a ketogenic diet. Dev Med Child Neurol.
1977 Aug;19(4):535-8.
Ketonemia and seizures: metabolic and anticonvulsant effects of two
ketogenic diets in childhood epilepsy. Pediatr Res. 1976
May;10(5):536-40.
Ketogenic diet containing medium-chain triglycerides. J Am Diet Assoc.
1973 Mar;62(3):285-90.
Medium-chain triglycerides as a therapy for intractable childhood
epilepsy. Neurology. 1971 Nov;21(11):1097-103.
Hospital Patient Care/Enteral and Parenteral Nutrition
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An enteral therapy containing medium-chain triglycerides and hydrolyzed
peptides reduces postprandial pain associated with chronic pancreatitis.
Pancreatology. 2003;3(1):36-40.
Clinical and metabolic effects of two lipid emulsions on the parenteral
nutrition of septic patients. Nutrition. 2002 Feb;18(2):134-8.
Metabolic effects of medium-chain triglycerides in parenteral nutrition
after surgery Zhonghua Wai Ke Za Zhi. 2001 Sep;39(9):694-7.
Medium-chain triglycerides inhibit free radical formation and TNF-alpha
production in rats given enteral ethanol. Am J Physiol Gastrointest
Liver Physiol 2000 Mar;278(3):G467-76.
Long chain versus medium chain lipids in patients with ARDS: effects on
pulmonary haemodynamics and gas exchange. Intensive Care Med. 1998
Oct;24(10):1029-33.
Medium-chain compared with long-chain triacylglycerol emulsions enhance
macrophage response and increase mucosal mass in parenterally fed rats.
Am J Clin Nutr. 1998 Jun;67(6):1265-72.
Decreased fat and nitrogen losses in patients with AIDS receiving
medium-chain-triglyceride-enriched formula vs those receiving
long-chain-triglyceride-containing formula. J Am Diet Assoc. 1997
Jun;97(6):605-11.
Nutritional management of the critically ill neurologic patient. Crit
Care Clin. 1997 Jan;13(1):39-49.
Efficacy of different triglycerides in total parenteral nutrition for
preventing atrophy of the gut in traumatized rats. JPEN J Parenter
Enteral Nutr. 1997 Jan-Feb;21(1):21-6.
Parenteral nutrition in the critically ill: use of a medium chain
triglyceride emulsion. Intensive Care Med 1993;19(2):89-95.
A comparison of medium-chain and long-chain triglycerides in surgical
patients. Ann Surg. 1993 Feb;217(2):175-84.
Insulinotropic potency of lauric acid: a metabolic rationale for medium
chain fatty acids (MCF) in TPN formulation. J Surg Res. 1992
Apr;52(4):328-33.
Long-chain versus medium and long-chain triglyceride-based fat emulsion
in parenteral nutrition of severe head trauma patients.
Infusionstherapie. 1990 Oct;17(5):246-8.
Comparison of medium and long chain triglyceride metabolism in intensive
care patients on parenteral nutrition. Intensive Care Med.
1989;15(4):250-4.
Clinical and experimental effects of medium-chain-triglyceride-based fat
emulsions--a review. Clin Nutr. 1989 Oct;8(5):223-35.
Medium chain triglycerides and structured lipids as unique nonglucose
energy sources in hyperalimentation. Lipids. 1987 Jun;22(6):421-3.
The metabolic consequences of infusing emulsions containing medium chain
triglycerides for parenteral nutrition: a comparative study with
conventional lipid. Ann R Coll Surg Engl. 1986 May;68(3):119-21.
Metabolism/Energy
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Medium- versus long-chain triglycerides for 27 days increases fat
oxidation and energy expenditure without resulting in changes in body
composition in overweight women. Int J Obes Relat Metab Disord. 2003
Jan;27(1):95-102.
Larger diet-induced thermogenesis and less body fat accumulation in rats
fed medium-chain triacylglycerols than in those fed long-chain
triacylglycerols. J Nutr Sci Vitaminol (Tokyo). 2002 Dec;48(6):524-9.
Comparison of diet-induced thermogenesis of foods containing medium-
versus long-chain triacylglycerols. J Nutr Sci Vitaminol (Tokyo). 2002
Dec;48(6):536-40.
The thermic effect is greater for structured medium- and long-chain
triacylglycerols versus long-chain triacylglycerols in healthy young
women. Metabolism. 2001 Jan;50(1):125-30.
Swimming endurance capacity of mice is increased by chronic consumption
of medium-chain triglycerides. J Nutr. 1995 Mar;125(3):531-9.
Postprandial thermogenesis in lean and obese subjects after meals
supplemented with medium-chain and long-chain triglycerides. Am J Clin
Nutr. 1991 May;53(5):1130-3.
Thermogenesis in humans during overfeeding with medium-chain
triglycerides. Metabolism. 1989 Jul;38(7):641-8.
Role of brown adipose tissue in thermogenesis induced by overfeeding a
diet containing medium chain triglyceride. Lipids. 1987 Jun;22(6):442-4.
Thermic effect of medium-chain and long-chain triglycerides in man. Am J
Clin Nutr. 1986 Nov;44(5):630-4.
Enhanced thermogenesis and diminished deposition of fat in response to
overfeeding with diet containing medium chain triglyceride. Am J Clin
Nutr. 1982 Apr;35(4):678-82.
Weight
Management
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Effects of dietary coconut oil on the biochemical and anthropometric
profiles of women presenting abdominal obesity. Lipids. 2009;
Jul;44(7):593-601; Epub 2009 May 13
Weight-loss diet that includes consumption of medium-chain
triacylglycerol oil leads to a greater rate of weight and fat mass loss
than does olive oil. Am J Clin Nutr. 2008 Mar;87(3):621-6.
Effects of dietary medium-chain triglyceride on weight loss and insulin
sensitivity in a group of moderately overweight free-living type 2
diabetic Chinese subjects. Metabolism. 2007 Jul;56(7):985-91.
Dietary fats, teas, dairy, and nuts: potential functional foods for
weight control?
Am J Clin Nutr. 2005
Jan;81(1):7-15.
Effect of dietary medium- and long-chain triacylglycerols (MLCT) on
accumulation of body fat in healthy humans. Asia Pac J Clin Nutr.
2003;12(2):151-60.
Greater rise in fat oxidation with medium-chain triglyceride consumption
relative to long-chain triglyceride is associated with lower initial
body weight and greater loss of subcutaneous adipose tissue. Int J Obes
Relat Metab Disord. 2003 Dec;27(12):1565-71.
Medium-chain triglycerides increase energy expenditure and decrease
adiposity in overweight men. Obes Res. 2003 Mar;11(3):395-402.
Consumption of an oil composed of medium chain triacyglycerols,
phytosterols, and N-3 fatty acids improves cardiovascular risk profile
in overweight women. Metabolism. 2003 Jun;52(6):771-7.
Medium- versus long-chain triglycerides for 27 days increases fat
oxidation and energy expenditure without resulting in changes in body
composition in overweight women. Int J Obes Relat Metab Disord. 2003
Jan;27(1):95-102.
Physiological effects of medium-chain triglycerides: potential agents in
the prevention of obesity. J Nutr. 2002 Mar;132(3):329-32.
Value of VLCD supplementation with medium chain triglycerides. Int J
Obes Relat Metab Disord. 2001 Sep;25(9):1393-400.
Dietary medium-chain triacylglycerols suppress accumulation of body fat
in a double-blind, controlled trial in healthy men and women. J Nutr.
2001 Nov;131(11):2853-9.
Effects of medium-chain fatty acids on body composition and protein
metabolism in overweight rats. J Physiol Biochem. 2000 Dec;56(4):337-46.
Endogenous fat oxidation during medium chain versus long chain
triglyceride feeding in healthy women. Int J Obes Relat Metab Disord.
2000 Sep;24(9):1158-66.
Medium chain fatty acid metabolism and energy expenditure: obesity
treatment implications. Life Sci. 1998;62(14):1203-15.
Covert manipulation of the ratio of medium- to long-chain triglycerides
in isoenergetically dense diets: effect on food intake in ad libitum
feeding men. Int J Obes Relat Metab Disord. 1996 May;20(5):435-44.
The role of oils containing triacylglycerols and medium-chain fatty
acids in the dietary treatment of obesity. The effect on resting energy
expenditure and serum lipids. Cas Lek Cesk. 1994 Jun 13;133(12):373-5.
Hypocaloric feeding in obese women: metabolic effects of medium-chain
triglyceride substitution. Am J Clin Nutr. 1989 Feb;49(2):326-30.
Overfeeding with medium-chain triglyceride diet results in diminished
deposition of fat. Am J Clin Nutr. 1983 Jan;37(1):1-4.
Enhanced thermogenesis and diminished deposition of fat in response to
overfeeding with diet containing medium chain triglyceride. Am J Clin
Nutr. 1982 Apr;35(4):678-82.
HIV/AIDS,
Liver Disease, and Other Health Concerns
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Diet supplemented with MCT oil in the management of childhood diarrhea.
Asia Pac J Clin Nutr. 2007;16(2):286-92.
Alcoholic fatty liver: its pathogenesis and mechanism of progression to
inflammation and fibrosis. Alcohol. 2004 Aug;34(1):9-19.
Protective effects of medium-chain triglycerides on the liver and gut in
rats administered endotoxin. Ann Surg. 2003 Feb;237(2):246-55.
Effects of dietary medium-chain triacylglycerols on serum lipoproteins
and biochemical parameters in healthy men. Biosci Biotechnol Biochem.
2002 Aug;66(8):1713-8.
Comparison of the fat elimination between long-chain triglycerides and
medium-chain triglycerides in rats with ischemic acute renal failure.
Ren. Fail. 2002 Jan;24(1):1-9.
Medium-chain triglycerides inhibit free radical formation and TNF-alpha
production in rats given enteral ethanol. Am J Physiol Gastrointest
Liver Physiol 2000 Mar;278(3):G467-76.
Review of the toxicologic properties of medium-chain triglycerides. Food
Chem Toxicol 2000 Jan:38(1):79-98
Prevention of hyperlipidemic acute pancreatitis during pregnancy with
medium-chain triglyceride nutritional support. Int J Pancreatol. 1998
Jun;23(3):187-92.
Decreased fat and nitrogen losses in patients with AIDS receiving
medium-chain-triglyceride-enriched formula vs those receiving
long-chain-triglyceride-containing formula. J Am Diet Assoc. 1997
Jun;97(6):605-11.
Review: nutritional support for patients with cirrhosis. J Gastroenterol
Hepatol. 1997 Apr;12(4):282-6.
A medium chain triglyceride-based diet in patients with HIV and chronic
diarrhea reduces diarrhea and malabsorption: a prospective, controlled
trial. Nutrition. 1996 Nov-Dec;12(11-12):766-71.
Protective effect of coconut oil on renal necrosis occurring in rats fed
a methyl-deficient diet. Ren. Fail. 1995 Sep; 17 (5):525-37.
Opposite effects of dietary saturated and unsaturated fatty acids on
ethanol-pharmacokinetics, triglycerides and carnitines. J Am Coll Nutr.
1994 Aug:13 (4):338-43.
Pityriasis versicolor and sunscreens containing coconut oil. Lancet.
1987 Sep 19;2(8560):685-6.
Coconut: a review of its uses as they relate to the allergic individual.
Ann Allergy. 1983 Oct;51(4):472-81.
Oral treatment of carnitine myopathy. Lancet. 1977 Apr 16;1(8016):853.
Carnitine deficiency of skeletal muscle: report of a treated case.
Neurology. 1976 Jul;26(7):633-7.
Regression of alcoholic fatty liver in the rat by medium-chain
triglycerides. Am J Clin Nut. 25: Feb; 1972, pp. 175-81.
Medium Chain Triglycerides in Paediatric Practice. Arch Dis Child. 1970
August; 45(242): 445–452.
Antigenotoxicity of Dietary Coconut Oil: Clara Y. Lim-Sylianco, A.P.
Guevara, and Sylianco-Wu, Institute of Chemistry College of Science
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